In practice and despite Anfinsen’s dogma. the refolding of recombinant multiple SS-bonded proteins is famously difficult because misfolded species with non-native SS-bonds appear upon the oxidization of their cysteine residues. On the other hand. single SS-bond proteins are thought to be simple to refold because their cysteines have only one SS-bond partner. https://www.bekindtopets.com/hot-mega-Sweetlix-16-8-Meat-Maker-with-Rumensin-18-lb-limited-choice/