Abstract Background An important component of time course microarray studies is the identification of genes that demonstrate significant time-dependent variation in their expression levels. Until recently. available methods for performing such significance tests required replicates of individual time points. This paper describes a replicate-free method that was developed as part of a ... https://safeersappliancers.shop/product-category/smeg-dfd13tp3x-full-size-dishwasher-stainless-steel/