Abstract Background Although the chondroprotection of peroxisome proliferator-activated receptor α (PPARα) activation against osteoarthritis (OA) has been revealed. the regulatory mechanism of PPARα deficiency to aggravate osteoarthritic cartilage deterioration remains unclear. Here. we aimed to investigate whether and how autophagy is involved in OA pathological progression. https://crowssportes.shop/product-category/used-goal-set/